Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis.

Abstract

Normal cells respond appropriately to various signals, while sustaining proper developmental programs and tissue homeostasis. Inappropriate signal reception, response or attenuation, can upset the normal balance of signaling within cells, leading to dysfunction or tissue malformation. To understand the molecular mechanisms that regulate protein-kinase-based… (More)
DOI: 10.1242/jcs.063313

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