Regulation of microtubules in cell migration.

  title={Regulation of microtubules in cell migration.},
  author={Takashi Watanabe and Jun Noritake and Kozo Kaibuchi},
  journal={Trends in cell biology},
  volume={15 2},
Directional cell migration is a fundamental process in all organisms that is stringently regulated during tissue development, chemotaxis and wound healing. Migrating cells have a polarized morphology with an asymmetrical distribution of signaling molecules and the cytoskeleton. Microtubules are indispensable for the directional migration of certain cells. Recent studies have shown that Rho family GTPases, which are key regulators of cell migration, affect microtubules, in addition to the actin… CONTINUE READING

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