Regulation of microRNA-1288 in colorectal cancer: altered expression and its clinicopathological significance.

@article{Gopalan2014RegulationOM,
  title={Regulation of microRNA-1288 in colorectal cancer: altered expression and its clinicopathological significance.},
  author={Vinod Gopalan and Suja Pillai and Faeza Ebrahimi and A. Salajegheh and Tommy Lam and Tran K Le and Nicole Langsford and Y. -H. Ho and Robert Anthony Smith and Alfred King-Yin Lam},
  journal={Molecular carcinogenesis},
  year={2014},
  volume={53 Suppl 1},
  pages={E36-44}
}
We aim to examine the miR-1288 expression in cancer cell lines and a large cohort of patients with colorectal cancer. Two colon cancer cell lines (SW480 and SW48) and one normal colonic epithelial cell line (FHC) were recruited. The miRNA expressions of miR-1288 were tested on these cell lines by using quantitative real-time polymerase chain reaction (qRT-PCR). An exogenous miR-1288 (mimic) was used to detect cell proliferation and cell cycle changes in SW480 using MTT calorimetric assay and… CONTINUE READING

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