Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells.

Abstract

Merlin (moesin-ezrin-radixin like protein), the product of neurofibromatosis type 2 gene, was primarily recognized as a tumor suppressor, but it also functions as a membrane-cytoskeletal linker and regulator of multiple signaling pathways. The activity and localization of merlin is regulated by head to tail folding that is controlled by phosphorylation of… (More)
DOI: 10.1016/j.biocel.2016.11.010

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