Regulation of membrane traffic by phosphoinositide 3-kinases.

@article{Lindmo2006RegulationOM,
  title={Regulation of membrane traffic by phosphoinositide 3-kinases.},
  author={Karine Lindmo and Harald Stenmark},
  journal={Journal of cell science},
  year={2006},
  volume={119 Pt 4},
  pages={
          605-14
        }
}
Phosphoinositide (PI) 3-kinases control essential cellular functions such as cytoskeletal dynamics, signal transduction and membrane trafficking. FYVE, PX and PH domains mediate the binding of effector proteins to the lipid products of PI 3-kinases. Recent studies have provided significant insights into the roles of PI 3-kinases, their catalytic products and their downstream effectors in membrane trafficking. Class I and II PI 3-kinases trigger receptor-induced trafficking processes, such as… CONTINUE READING

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