Regulation of melanin-concentrating hormone receptor 1 signaling by RGS8 with the receptor third intracellular loop.


Melanin-concentrating hormone (MCH) receptor 1 (MCH1R) belongs to the class A G protein-coupled receptors (GPCRs). The MCH-MCH1R system plays a central role in energy metabolism, and thus the regulation of signaling pathways activated by this receptor is of particular interest. Regulator of G protein signaling (RGS) proteins work by increasing the GTPase… (More)
DOI: 10.1016/j.cellsig.2008.07.019


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