Regulation of meiotic recombination and prophase I progression in mammals.

  title={Regulation of meiotic recombination and prophase I progression in mammals.},
  author={Paula E. Cohen and Jeffrey W Pollard},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={23 11},
Meiosis is the process by which diploid germ cells divide to produce haploid gametes for sexual reproduction. The process is highly conserved in eukaryotes, however the recent availability of mouse models for meiotic recombination has revealed surprising regulatory differences between simple unicellular organisms and those with increasingly complex genomes. Moreover, in these higher eukaryotes, the intervention of physiological and sex-specific factors may also influence how meiotic… CONTINUE READING

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