Regulation of mechanical signals in bone.

  title={Regulation of mechanical signals in bone.},
  author={Stefan Judex and Sonam Gupta and Clinton T. Rubin},
  journal={Orthodontics & craniofacial research},
  volume={12 2},
OBJECTIVES Response of the skeleton to application and removal of specific mechanical signals is discussed. Anabolic effects of high-frequency, low-magnitude vibrations, a mechanical intervention with a favorable safety profile, as well as the modulation of bone loss by genetic and epigenetic factors during disuse are highlighted. METHODS Review. RESULTS Bone responds to a great variety of mechanical signals and both high- and low-magnitude stimuli can be sensed by the skeleton. The ability… CONTINUE READING
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