Regulation of mammalian acetyl-coenzyme A carboxylase.

@article{Kim1997RegulationOM,
  title={Regulation of mammalian acetyl-coenzyme A carboxylase.},
  author={Keejong Kim},
  journal={Annual review of nutrition},
  year={1997},
  volume={17},
  pages={
          77-99
        }
}
Long-chain fatty acids are involved in all aspects of cellular structure and function. For controlling amounts of fatty acids, cells are endowed with two acetyl-coenzyme A carboxylase (ACC) systems. ACC-alpha is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta is believed to control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. Phosphorylation and dephosphorylation of ACC-alpha cause enzyme… CONTINUE READING
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