Regulation of major histocompatibility complex class I gene expression in thyroid cells. Role of the cAMP response element-like sequence.

@article{Saji1997RegulationOM,
  title={Regulation of major histocompatibility complex class I gene expression in thyroid cells. Role of the cAMP response element-like sequence.},
  author={Motoyasu Saji and Minho Shong and Giorgio Napolitano and Lisa A. Palmer and S i Taniguchi and Masayuki Ohmori and Masanori Ohta and Koichi Suzuki and S L Kirshner and Cesidio Giuliani and Dinah Singer and Leonard D. Kohn},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 32},
  pages={20096-107}
}
The major histocompatibility complex (MHC) class I gene cAMP response element (CRE)-like site, -107 to -100 base pairs, is a critical component of a previously unrecognized silencer, -127 to -90 bp, important for thyrotropin (TSH)/cAMP-mediated repression in thyrocytes. TSH/cAMP induced-silencer activity is associated with the formation of novel complexes with the 38-base pair silencer, whose appearance requires the CRE and involves ubiquitous and thyroid-specific proteins as follows: the CRE… CONTINUE READING
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…