Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation.

@article{Maitra2000RegulationOL,
  title={Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation.},
  author={Subir R. Maitra and Songbai Wang and M. Raafat El-Maghrabi and Mark C. Henry},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2000},
  volume={7 7},
  pages={731-8}
}
UNLABELLED The authors have recently demonstrated that increased gene expression of glucose-6-phosphatase (Glu-6-Pase) in hemorrhagic hypotension (HH) and following lactated Ringer's resuscitation (LR) is associated with a decrease in insulin and an increase in corticosterone concentrations. OBJECTIVE To evaluate the in-vivo role of hormones the authors used insulin (IN), phentolamine and propranolol (PP) as an adrenergic blocker, and cyclic somatostatin (CS) as a glucagon blocker to prevent… CONTINUE READING