Regulation of lipoprotein lipase by Angptl4

@article{Dijk2014RegulationOL,
  title={Regulation of lipoprotein lipase by Angptl4},
  author={Wieneke Dijk and Sander Kersten},
  journal={Trends in Endocrinology \& Metabolism},
  year={2014},
  volume={25},
  pages={146-155}
}
Triglyceride (TG)-rich chylomicrons and very low density lipoproteins (VLDL) distribute fatty acids (FA) to various tissues by interacting with the enzyme lipoprotein lipase (LPL). The protein angiopoietin-like 4 (Angptl4) is under sensitive transcriptional control by FA and the FA-activated peroxisome proliferator activated receptors (PPARs), and its tissue expression largely overlaps with that of LPL. Growing evidence indicates that Angptl4 mediates the physiological fluctuations in LPL… 
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