Regulation of lipolysis by human adipose tissue in hyperthyroidism.

  title={Regulation of lipolysis by human adipose tissue in hyperthyroidism.},
  author={Peter Arner and Anders Wennlund and Jan Ostman},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={48 3},
The effects of noradrenaline (NA) and isopropyl-noradrenaline (ISNA) on glycerol release and cAMP levels in sc adipose tissue were studied in vitro in 27 patients with hyperthyroidism. In 11 patients, the studies were repeated after 6--12 months of treatment for hyperthyroidism. A third group comprised 21 euthyroid patients otherwise healthy except for morbid obesity. The lipolytic response to ISNA, observed in untreated thyrotoxic patients, was found to be reduced by 30% when the patients were… CONTINUE READING