Regulation of lipin1 by nutritional status, adiponectin, sex and pituitary function in rat white adipose tissue

@article{Gonzlez2012RegulationOL,
  title={Regulation of lipin1 by nutritional status, adiponectin, sex and pituitary function in rat white adipose tissue},
  author={Carmen R. Gonz{\'a}lez and Marta G Novelle and Jorge Eduardo Caminos and Mar{\'i}a Jes{\'u}s V{\'a}zquez and Carlos Di{\'e}guez},
  journal={Physiology & Behavior},
  year={2012},
  volume={105},
  pages={777-783}
}
  • Carmen R. González, Marta G Novelle, +2 authors Carlos Diéguez
  • Published in Physiology & Behavior 2012
  • Biology, Medicine
  • Lipin1 is a member of the lipin protein family that plays an important role in the regulation of lipid metabolism. The endogenous role of lipin1 was demonstrated by the fact that mutations in lipin1 caused lipodystrophy and metabolic disorders. The aim of this study was to assess the influence of nutritional status, pregnancy, insulin-sensitizers and pituitary hormones on lipin1 mRNA levels in adipose tissue of rats. Lipin1 gene expression was induced in conditions of hypoleptinemia (fasting… CONTINUE READING

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