Regulation of lens cell growth and polarity by an embryo-specific growth factor and by inhibitors of lens cell proliferation and differentiation.

@article{Hyatt1993RegulationOL,
  title={Regulation of lens cell growth and polarity by an embryo-specific growth factor and by inhibitors of lens cell proliferation and differentiation.},
  author={Geoffrey Hyatt and David C. Beebe},
  journal={Development},
  year={1993},
  volume={117 2},
  pages={701-9}
}
We used a double-label method, which monitors the rate at which cells enter S-phase of the cell cycle, to identify factors that control the growth of chicken embryo lens epithelial cells in vivo. With this assay, we identified a mitogen for lens epithelial cells in the anterior segment of the embryonic eye. When the anterior chamber was opened briefly, by… CONTINUE READING