Regulation of latency to lytic life cycle: multiple tricks by KSHV RTA

Abstract

The herpesviruses are large enveloped DNA viruses that infect a wide spectrum hosts including human being. A key characteristic of all herpesviruses is their ability to establish life-time latency within the infected host and to periodically reactivate and enter the lytic replication to produce infectious virus progeny. During latency the 120– 300 kb double… (More)
DOI: 10.1007/s11515-010-0046-1

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