Regulation of large coronary arteries by increases in myocardial metabolic demands in conscious dogs.

@article{Macho1981RegulationOL,
  title={Regulation of large coronary arteries by increases in myocardial metabolic demands in conscious dogs.},
  author={Pilar Macho and Thomas H. Hintze and Stephen F. Vatner},
  journal={Circulation research},
  year={1981},
  volume={49 3},
  pages={594-9}
}
In order to assess the effects of increasing myocardial metabolic demand on the large epicardial coronary arteries, we measured left circumflex coronary artery diameter (ultrasonic transit time technique) and blood flow in conscious dogs with chronically implanted transducers. Myocardial oxygen consumption was increased by pacing-induced tachycardia and aortic constriction, and monitored by multiplying left circumflex coronary arterial blood flow by coronary arterio-venous oxygen content… CONTINUE READING