Regulation of keratinocyte growth factor gene expression in human skin fibroblasts.

  title={Regulation of keratinocyte growth factor gene expression in human skin fibroblasts.},
  author={Alice M. Tang and B. A. Gilchrest},
  journal={Journal of dermatological science},
  volume={11 1},
Human keratinocyte growth factor (KGF) is a recently identified mitogen for epithelial cells produced by normal stromal fibroblasts. KGF has been shown to stimulate keratinocyte migration and promote re-epithelialization of skin suggesting a critical role for KGF in wound healing. To understand how KGF might be regulated during wound healing, we examined the ability of the pro-inflammatory cytokines interleukin-1 alpha (IL-1 alpha), interleukin-1 beta (IL-1 beta) interleukin-6 (IL-6), tumor… CONTINUE READING


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Highly Influenced

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