Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation.

Abstract

Given the important relationship between O2 and iron (Fenton chemistry) a study was undertaken to characterize the effects of hypoxia, as well as subsequent reoxygenation, on the iron-regulatory proteins 1 and 2 (IRP1 and IRP2) in a rat hepatoma cell line. IRP1 and IRP2 are cytosolic RNA-binding proteins that bind RNA stem-loops located in the 5'- or 3… (More)

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Cite this paper

@article{Hanson1998RegulationOI, title={Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation.}, author={Erin Hanson and Edgar Leibold}, journal={The Journal of biological chemistry}, year={1998}, volume={273 13}, pages={7588-93} }