Regulation of ion transport by the NHERF family of PDZ proteins.

@article{Shenolikar2004RegulationOI,
  title={Regulation of ion transport by the NHERF family of PDZ proteins.},
  author={Shirish S Shenolikar and James W Voltz and Rochelle Cunningham and Edward J. Weinman},
  journal={Physiology},
  year={2004},
  volume={19},
  pages={362-9}
}
NHERFs are the best-studied apical PDZ proteins that are highly expressed in epithelial cells. Molecular and cellular studies over the past decade show that NHERFs regulate the targeting or trafficking of ion transporters and other membrane proteins and transduce physiological and pathophysiological signals that regulate ion homeostasis in mammals.