Regulation of intrinsic regenerative properties and axonal plasticity in cerebellar Purkinje cells.

@article{Rossi2001RegulationOI,
  title={Regulation of intrinsic regenerative properties and axonal plasticity in cerebellar Purkinje cells.},
  author={Ferdinando Dott. Rossi and Annalisa Buffo and Piergiorgio Strata},
  journal={Restorative neurology and neuroscience},
  year={2001},
  volume={19 1-2},
  pages={85-94}
}
Axon regeneration in the mammalian brain requires that injured neurons upregulate a specific set of growth-associated genes. To investigate the mechanisms that control the intrinsic growth properties of adult central neurons, we have examined the response to injury and regenerative potential of different cerebellar and precerebellar neuron populations. Axotomised neurons in the inferior olive, deep cerebellar nuclei and lateral reticular nucleus upregulate growth-associated molecules and… CONTINUE READING

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