Regulation of intracellular pH in sheep cardiac Purkinje fibre: interactions among Na+, H+, and Ca2+1.

@article{Kaila1987RegulationOI,
  title={Regulation of intracellular pH in sheep cardiac Purkinje fibre: interactions among Na+, H+, and Ca2+1.},
  author={Kai Kaila and Richard D. Vaughan-Jones and C Bountra},
  journal={Canadian journal of physiology and pharmacology},
  year={1987},
  volume={65 5},
  pages={963-9}
}
Experiments were performed on sheep cardiac Purkinje fibres using pH- and sodium-selective microelectrodes, while simultaneously measuring tension, to determine if the fall in intracellular pH (pHi) following a rise in intracellular Na+ activity (aiNa) is caused by inhibition or reversal of acid extrusion on Na+-H+ exchange. A rise in aiNa was induced… CONTINUE READING