Regulation of intracellular free calcium concentration during heterocyst differentiation by HetR and NtcA in Anabaena sp. PCC 7120.

@article{Shi2006RegulationOI,
  title={Regulation of intracellular free calcium concentration during heterocyst differentiation by HetR and NtcA in Anabaena sp. PCC 7120.},
  author={Yunming Shi and Weixing Zhao and Wei Zhang and Zi Ye and Jindong Zhao},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 30},
  pages={11334-9}
}
Calcium ions are important to some prokaryotic cellular processes, such as heterocyst differentiation of cyanobacteria. Intracellular free Ca(2+)concentration, [Ca(2+)](i), increases several fold in heterocysts and is regulated by CcbP, a Ca(2+)-binding protein found in heterocyst-forming cyanobacteria. We demonstrate here that CcbP is degraded by HetR, a serine-type protease that controls heterocyst differentiation. The degradation depends on Ca(2+) and appears to be specific because HetR did… CONTINUE READING

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