Regulation of intracellular calcium in human breast cancer cells

  title={Regulation of intracellular calcium in human breast cancer cells},
  author={Dr. Igor N. Sergeev and William B. Rhoten},
Regulation of intracellular Ca2+ in breast cancer may be important in modulating cell proliferation, differentiation, apoptosis, and cytotoxicity, as well as contributing to mechanisms of action of anticancer agents. One of these agents, the steroid hormone 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], is intimately involved in maintaining cellular Ca2+ homeostasis. The purpose of this study was to investigate Ca2+ regulatory pathways in breast cancer cells and to determine the role of 1,25(OH)2D3 in… CONTINUE READING
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Anticancer Res. 14, 1549–1556

  • J. Bergmann, I. Junghahn, H. Brachwitz, P. Langen
  • Cancer Cells/Sergeev and Rhoten Vol. 9,
  • 1994
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