Regulation of interferon-gamma, interleukin-4 and interleukin-2 by Schizonepeta tenuifolia through differential effects on nuclear factor-kappaB, NFATc2 and STAT4/6.

@article{Kang2010RegulationOI,
  title={Regulation of interferon-gamma, interleukin-4 and interleukin-2 by Schizonepeta tenuifolia through differential effects on nuclear factor-kappaB, NFATc2 and STAT4/6.},
  author={Hee Kang and Ja-Young Moon and Nak-Won Sohn},
  journal={Experimental biology and medicine},
  year={2010},
  volume={235 2},
  pages={
          230-6
        }
}
Contact with antigen on T-cells is made via the T-cell receptor/CD3 complex plus CD28, resulting in the production of cytokines including interleukin (IL)-2, IL-4 and interferon (IFN)-gamma. In particular, dysregulation of IFN-gamma and IL-4 accounts in part for organ-specific autoimmune diseases, allergic inflammation and other chronic inflammatory disorders. The dried above-ground parts of Schizonepeta tenuifolia Briq are used for the treatment of common cold and skin rashes observed in… CONTINUE READING
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