Regulation of insulin-like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone.

Abstract

Glucocorticoids inhibit the proliferation, but induce the differentiation, of bone marrow stromal cells into osteoblast-like cells. The mechanisms, however, are still conjectural. Since insulin-like growth factors (IGFs) have profound effects on osteoblast growth and differentiation, it is possible that glucocorticoids exert their effects on bone marrow… (More)

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@article{Cheng1998RegulationOI, title={Regulation of insulin-like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone.}, author={Siu Lung Cheng and S F Zhang and Sumathy Mohan and Fernando Lecanda and Aurora Fausto and Anton Hunt and Ernesto Canalis and Louis V. Avioli}, journal={Journal of cellular biochemistry}, year={1998}, volume={71 3}, pages={449-58} }