Regulation of inflammation by the antioxidant haem oxygenase 1.

@article{Campbell2021RegulationOI,
  title={Regulation of inflammation by the antioxidant haem oxygenase 1.},
  author={Nicole K Campbell and Hannah K Fitzgerald and Aisling Dunne},
  journal={Nature reviews. Immunology},
  year={2021}
}
Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of haem, is primarily considered an antioxidant, and has long been overlooked by immunologists. However, research over the past two decades in particular has demonstrated that HO-1 also exhibits numerous anti-inflammatory properties. These emerging immunomodulatory functions have made HO-1 an appealing target for treatment of diseases characterized by high levels of chronic inflammation. In this Review, we present an… 
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