Regulation of inflammation by cannabinoids, the endocannabinoids 2‐arachidonoyl‐glycerol and arachidonoyl‐ethanolamide, and their metabolites

@article{Turcotte2015RegulationOI,
  title={Regulation of inflammation by cannabinoids, the endocannabinoids 2‐arachidonoyl‐glycerol and arachidonoyl‐ethanolamide, and their metabolites},
  author={Caroline Turcotte and François C Chouinard and Julie S. Lefebvre and Nicolas Flamand},
  journal={Journal of Leukocyte Biology},
  year={2015},
  volume={97}
}
2‐Arachidonoyl‐glycerol (2‐AG) and arachidonyl‐ethanolamide (AEA) are endocannabinoids that have been implicated in many physiologic disorders, including obesity, metabolic syndromes, hepatic diseases, pain, neurologic disorders, and inflammation. Their immunomodulatory effects are numerous and are not always mediated by cannabinoid receptors, reflecting the presence of an arachidonic acid (AA) molecule in their structure, the latter being the precursor of numerous bioactive lipids that are pro… Expand
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TLDR
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