Regulation of inflammasomes by autophagy.

  title={Regulation of inflammasomes by autophagy.},
  author={Tatsuya Saitoh and Shizuo Akira},
  journal={The Journal of allergy and clinical immunology},
  volume={138 1},
Inflammasomes detect pathogen-associated molecular patterns to induce inflammatory innate immune responses and play a key role in host defense against infectious agents. However, inflammasomes are often wrongly activated by metabolites, amyloids, and environmental irritants. This induces massive inflammation, causing severe tissue damage, and results in the… CONTINUE READING