Regulation of imprinted DNA methylation.

@article{Holmes2006RegulationOI,
  title={Regulation of imprinted DNA methylation.},
  author={Rebecca M. Holmes and Paul D. Soloway},
  journal={Cytogenetic and genome research},
  year={2006},
  volume={113 1-4},
  pages={
          122-9
        }
}
DNA methylation is an essential enzymatic modification in mammals. This common epigenetic mark occurs predominantly at the fifth carbon of cytosines within the palindromic dinucleotide 5'-CpG-3'. The majority of methylated CpGs are located within repetitive elements including centromeric repeats, satellite sequences and gene repeats encoding ribosomal RNAs. CpG islands, frequently located at the 5' end of genes, are typically unmethylated. DNA methylation also occurs at imprinted genes which… CONTINUE READING
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