Regulation of immune cell homeostasis by type I interferons.

  title={Regulation of immune cell homeostasis by type I interferons.},
  author={Fabrizio Mattei and Giovanna Schiavoni and David F. Tough},
  journal={Cytokine & growth factor reviews},
  volume={21 4},
Although initially identified and best characterized for their role in innate antiviral defence, type I interferons (IFN-I) are also known to have an important impact on the adaptive immune response. In part, this is linked to another long-recognised property of IFN-I, namely their ability to modify cellular proliferation and survival. Here, we review the… CONTINUE READING