Regulation of human mesangial cell growth in culture by thromboxane A2 and prostacyclin.

@article{Men1990RegulationOH,
  title={Regulation of human mesangial cell growth in culture by thromboxane A2 and prostacyclin.},
  author={Paolo Men{\`e} and Hanna Emily Abboud and Michael J. Dunn},
  journal={Kidney international},
  year={1990},
  volume={38 2},
  pages={232-9}
}
Elevated eicosanoid biosynthesis characterizes certain forms of human and experimental glomerular proliferative disease. Thromboxane A2 (TxA2) and other prostaglandins (PG) act through specific receptors and mechanisms of intracellular signal transduction in human mesangial cells. We studied the actions of U-46619, a TxA2 mimetic which stimulates mesangial… CONTINUE READING