Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.

@article{Desfosss2005RegulationOH,
  title={Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.},
  author={Yan Desfoss{\'e}s and Mayra Solis and Qingnan Sun and Nathalie Grandvaux and Carine Van Lint and Ars{\`e}ne Burny and Anne Gatignol and Mark A. Wainberg and Rongtuan Lin and John Hiscott},
  journal={Journal of virology},
  year={2005},
  volume={79 14},
  pages={9180-91}
}
The major group of human immunodeficiency virus type 1 (HIV-1) strains that comprise the current global pandemic have diversified during their worldwide spread into at least 10 distinct subtypes, or clades. Subtype C predominates in sub-Saharan Africa and is responsible for the majority of worldwide HIV-1 infections, subtype B predominates in North America and Europe, and subtype E is prevalent in Southeast Asia. Significant amino acid variations have been observed among the clade-specific Tat… CONTINUE READING
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