Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro.

@article{Bartold1989RegulationOH,
  title={Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro.},
  author={P Mark Bartold},
  journal={Journal of periodontal research},
  year={1989},
  volume={24 5},
  pages={314-21}
}
Gingival overgrowth is an adverse side-effect seen in a proportion of patients taking cyclosporin-A which indicates that cyclosporine-A may modulate the activities of cells other than T lymphocytes. Therefore, the effect of cyclosporine on human gingival fibroblasts has been studied in vitro. Cyclosporine-A was found to stimulate DNA synthesis and the… CONTINUE READING