Regulation of human erythrocyte Na+/H+ exchange by soluble and particulate guanylate cyclase.

@article{Petrov1996RegulationOH,
  title={Regulation of human erythrocyte Na+/H+ exchange by soluble and particulate guanylate cyclase.},
  author={Victor V. Petrov and P F Lijnen},
  journal={The American journal of physiology},
  year={1996},
  volume={271 5 Pt 1},
  pages={C1556-64}
}
Guanylate cyclase activity in human erythrocytes is investigated by evaluating the intracellular guanosine 3',5'-cyclic monophosphate (cGMP) content in the presence of various agents that exert specific effects on soluble or particulate guanylate cyclase. The increase in the intraerythrocyte cGMP content by the soluble guanylate cyclase activators nitroprusside and NaNO2 suggests the presence of this enzyme in human erythrocytes. The effects of four different atrial natriuretic peptide (ANP… CONTINUE READING

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