Regulation of human epidermal melanocyte biology by beta-endorphin.

  title={Regulation of human epidermal melanocyte biology by beta-endorphin.},
  author={S{\"o}bia Kauser and Karin Uta Schallreuter and Anthony John Thody and C L Gummer and Desmond J. Tobin},
  journal={The Journal of investigative dermatology},
  volume={120 6},
beta-Endorphin is an opioid peptide cleaved from the precursor pro-hormone pro-opiomelanocortin, from which other peptides such as adrenocorticotropic hormone, beta-lipotropic hormone, and alpha-melanocyte-stimulating hormone are also derived. alpha-Melanocyte-stimulating hormone and adrenocorticotropic hormone are well documented to regulate human skin pigmentation via action at the melanocortin-1 receptor. Whereas plasma beta-endorphin is reported to increase after exposure to ultraviolet… CONTINUE READING


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