Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1).

@article{Dittel1993RegulationOH,
  title={Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1).},
  author={Bonnie N Dittel and James B. McCarthy and Elizabeth A. Wayner and Tucker W Lebien},
  journal={Blood},
  year={1993},
  volume={81 9},
  pages={2272-82}
}
Self-renewal and differentiation of B-cell precursors is dependent on interactions with bone marrow (BM) stromal cells and associated extracellular matrix. We have recently developed an interleukin (IL)-7-dependent, BM-derived stromal cell culture that supports the growth of normal human B-cell precursors. In the current study, we have characterized the constitutive expression, cytokine-regulated expression, and function of adhesion molecules on BM stromal cells that are critical for adhesion… CONTINUE READING
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References

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Showing 1-8 of 8 references

MP: Tumor cell surface a401 integrin mediates adhesion to vascular endothelium: Demonstration of an interaction with the N-terminal domains of INCAM-1 lo/ VCAM-I

DB Taichman, MI Cybulsky, +5 authors Bevilacqua
Cell Regul2:347, • 1991

B cell development in the bone marrow.

Seminars in immunology • 1990
View 1 Excerpt

VCAM-I on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA4/fibronectin binding

MJ Elices, L Osbom, +4 authors RR Lobb
site. Cell 60577, • 1990

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