Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise.

@article{Roepstorff2004RegulationOH,
  title={Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise.},
  author={Carsten Roepstorff and Bodil Vistisen and Morten Donsmark and Jakob Nis Nielsen and Henrik Galbo and Kevin A. Green and David Grahame Hardie and J\orgen F P Wojtaszewski and Erik A Richter and Bente Kiens},
  journal={The Journal of physiology},
  year={2004},
  volume={560 Pt 2},
  pages={551-62}
}
Hormone-sensitive lipase (HSL) catalyses the hydrolysis of myocellular triacylglycerol (MCTG), which is a potential energy source during exercise. Therefore, it is important to elucidate the regulation of HSL activity in human skeletal muscle during exercise. The main purpose of the present study was to investigate the role of 5'AMP-activated protein kinase (AMPK) in the regulation of muscle HSL activity and Ser565 phosphorylation (the presumed AMPK target site) in healthy, moderately trained… CONTINUE READING