Regulation of homocysteine metabolism and methylation in human and mouse tissues.

Abstract

Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Homocysteine (Hcy) metabolism involves multiple enzymes; however, tissue Hcy metabolism and its relevance to methylation remain unknown. Here, we established gene expression profiles of 8 Hcy metabolic and 12 methylation enzymes in 20 human and 19 mouse tissues through… (More)
DOI: 10.1096/fj.09-143651

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Cite this paper

@article{Chen2010RegulationOH, title={Regulation of homocysteine metabolism and methylation in human and mouse tissues.}, author={Natalie C. Chen and Fan Yang and Louis M Capecci and Ziyu Gu and Andrew I. Schafer and William Durante and Xiao Yang and Hong Wang}, journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year={2010}, volume={24 8}, pages={2804-17} }