Regulation of herpes simplex virus 1 replication using tumor-associated promoters.

Abstract

OBJECTIVE To investigate use of transcriptional regulatory elements (promoters) for tumor-associated antigens to achieve HSV-1 replication preferentially in cells that overexpress the tumor-associated antigens. SUMMARY BACKGROUND DATA An important advantage of replicating viruses for cancer therapy is their ability to simultaneously destroy tumor cells by… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.