• Medicine, Biology
  • Published in Journal of lipid research 1992

Regulation of hepatic secretion of very low density lipoprotein by dietary cholesterol.

@article{Fungwe1992RegulationOH,
  title={Regulation of hepatic secretion of very low density lipoprotein by dietary cholesterol.},
  author={Thomas V. Fungwe and Lauren M. Cagen and Henry G. Wilcox and Murray Heimberg},
  journal={Journal of lipid research},
  year={1992},
  volume={33 2},
  pages={
          179-91
        }
}
Male rats were fed a cholesterol-free diet or the same diet supplemented with either 0.05, 0.1, 0.25, 0.5, 1, or 2% C for 21 days to investigate the effects of cholesterol on secretion of very low density lipoprotein (VLDL). Cholesterol feeding increased plasma and hepatic concentrations of triglyceride (TG) and cholesteryl esters (CE) in a dose-dependent manner. Plasma VLDL and low density lipoprotein (LDL) lipids were elevated by cholesterol feeding, while the high density lipoprotein (HDL… CONTINUE READING

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