Corpus ID: 7697836

Regulation of hepatic glycine catabolism by glucagon.

@article{Jois1989RegulationOH,
  title={Regulation of hepatic glycine catabolism by glucagon.},
  author={M. Jois and B. Hall and K. Fewer and J. Brosnan},
  journal={The Journal of biological chemistry},
  year={1989},
  volume={264 6},
  pages={
          3347-51
        }
}
  • M. Jois, B. Hall, +1 author J. Brosnan
  • Published 1989
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • Glucagon stimulates 14CO2 production from [1-14C] glycine by isolated rat hepatocytes. Maximal stimulation (70%) of decarboxylation of glycine by hepatocytes was achieved when the concentration of glucagon in the medium reached 10 nM; half-maximal stimulation occurred at a concentration of about 2 nM. A lag period of 10 min was observed before the stimulation could be measured. Inclusion of beta-hydroxybutyrate (10 mM) or acetoacetate (10 mM) did not affect the magnitude of stimulation… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 13 CITATIONS

    Catabolism of arginine and ornithine in the perfused rat liver: effect of dietary protein and of glucagon.

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    Uptake and metabolism of propionate in the liver isolated from sheep treated with glucagon.

    VIEW 2 EXCERPTS
    CITES BACKGROUND & METHODS

    Glycine metabolism in animals and humans: implications for nutrition and health

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Production of 1-carbon units from glycine is extensive in healthy men and women.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-2 OF 2 REFERENCES

    Adu. Enzyme Regul

    • Cell. Biochem
    • 1976

    Hormonal Control o Gluconeogenesis (Kraus-FriedHampson

    • J. Biol. Chem
    • 1983