Regulation of hepatic apolipoprotein-B-containing lipoprotein secretion.

  title={Regulation of hepatic apolipoprotein-B-containing lipoprotein secretion.},
  author={Richard J. Pease and James M. Leiper},
  journal={Current opinion in lipidology},
  volume={7 3},
The overall secretion of hepatic lipid as VLDL may be regulated by (i) changing the number of particles secreted as a result of altering apolipoprotein B output and (ii) changing the degree of lipidation of the particles with triacylglycerol so that their diameters vary over a threefold range. Substantial progress has been made in understanding the pathway of triacylglycerol incorporation into VLDL. Less is understood about the processes that commit apolipoprotein B either to secretion or to… CONTINUE READING

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