Regulation of growth cone extension by SNARE proteins.

@article{Kimura2003RegulationOG,
  title={Regulation of growth cone extension by SNARE proteins.},
  author={Kazushi Kimura and Akira Mizoguchi and Chizuka Ide},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2003},
  volume={51 4},
  pages={429-33}
}
Recent studies have suggested that the soluble N-ethylmaleimide-sensitive factor attached protein (SNAP) receptor (SNARE)-mediated membrane fusion system is involved in vesicle fusion with the surface plasma membrane, which leads to neurite elongation. There have been several reports analyzing the effects of neurite outgrowth by inhibition of SNAREs. We studied this mechanism by overexpressing GFP-fusion SNAREs including VAMP-2, SNAP-25A, and syntaxin1A in PC12 cells to investigate the role of… CONTINUE READING
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VAMP - 2 promotes neurite elongation and SNAP25 A increases neurite sprouting in PC 12 cells

  • M Shirasu, K Kimura, +4 authors Y Hirasawa
  • Neurosci Res
  • 2000
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