Regulation of glycolytic flux by coronary flow in guinea pig heart. Role of vascular endothelial cell glycocalyx.

@article{Suarez1991RegulationOG,
  title={Regulation of glycolytic flux by coronary flow in guinea pig heart. Role of vascular endothelial cell glycocalyx.},
  author={Jorge M Suarez and Rafael Rubio},
  journal={The American journal of physiology},
  year={1991},
  volume={261 6 Pt 2},
  pages={H1994-2000}
}
Hemodynamic forces continuously act on endothelial cell lining of blood vessels. Blood flow, perfusing pressure, and shear stress are known to induce the release of bioactive substances from the endothelium. Furthermore, coronary flow (CF) is a well-known stimulant of myocardial contraction. Our concern was whether other Ca(2+)-dependent responses like glycolytic flux (Gf) were also CF dependent. For this purpose, isolated guinea pig hearts were perfused with a medium containing 5 mM 3-[3H… CONTINUE READING

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