Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.

@article{Koutsilieri1997RegulationOG,
  title={Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.},
  author={Eleni Koutsilieri and Mario E. G{\"o}tz and Sieghart Sopper and Ursula S Sauer and Monika Demuth and Volker ter Meulen and Peter Franz Riederer},
  journal={Journal of neurovirology},
  year={1997},
  volume={3 5},
  pages={342-9}
}
The aim of the present study was to assess the toxic potential of drugs of abuse and other neuropharmacological agents in the pathogenesis of AIDS dementia complex (ADC), the neurological complication of AIDS. Neuroblastoma and glioblastoma cell lines expressing the dopamine transporter, as well as primary macrophages exposed to human immunodeficiency virus-1 (HIV-1), were used to investigate the possibility of any synergistic effect between the mode of toxicity of such substances and virus… CONTINUE READING
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