Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen.

@article{Pawlak2005RegulationOG,
  title={Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen.},
  author={Justyna Pawlak and Veronica I. Brito and E. W. Udo K{\"u}ppers and Cordian Beyer},
  journal={Brain research. Molecular brain research},
  year={2005},
  volume={138 1},
  pages={1-7}
}
Estrogen influences neuronal development and a broad spectrum of neural functions. In addition, several lines of evidence suggest a role as neuroprotective factor for estrogen in the CNS. Neuroprotection can result from direct estrogen-neuron interactions or be mediated indirectly involving the regulation of physiological properties of nonneuronal cells, such as astrocytes and microglia. Increased l-glutamate levels are associated with neurotoxic and neurodegenerative processes in the brain… CONTINUE READING