Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes.

@article{Zhang2007RegulationOG,
  title={Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes.},
  author={Hong-Mei Zhang and Shao‐Rui Chen and Hui-Lin Pan},
  journal={Journal of neurophysiology},
  year={2007},
  volume={97 1},
  pages={
          102-9
        }
}
Activation of spinal muscarinic acetylcholine receptors (mAChRs) produces analgesia and inhibits dorsal horn neurons through potentiation of GABAergic/glycinergic tone and inhibition of glutamatergic input. To investigate the mAChR subtypes involved in the inhibitory effect of mAChR agonists on glutamate release, evoked excitatory postsynaptic currents (eEPSCs) were recorded in lamina II neurons using whole cell recordings in rat spinal cord slices. The nonselective mAChR agonist oxotremorine-M… 
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References

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