Regulation of glucose transport in the NIH 3T3 L1 preadipocyte cell line by TCDD.

@article{Olsen1994RegulationOG,
  title={Regulation of glucose transport in the NIH 3T3 L1 preadipocyte cell line by TCDD.},
  author={Hendrik Olsen and Essam Enan and Fumio Matsumura},
  journal={Environmental Health Perspectives},
  year={1994},
  volume={102},
  pages={454 - 458}
}
This study examined the changes in cellular glucose uptake induced by 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) as measured by quantification of intracellular radioactivity in the NIH 3T3 L1 preadipocyte cell line after a 30-minute incubation with the non-metabolizable radioactive analogue of glucose, 3-O-methyl-D-[1-3H] glucose. Treatment of differentiated NIH 3T3 L1 cells with TCDD produced a time- and dose-dependent decrease in the cellular uptake of glucose. Treatment of cells for 3 hr… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 25 REFERENCES

Induction of fatty acid synthetase synthesis in differentiating 3 T 3L 1 preadipocytes

  • AK Student, RY Hsu
  • J Biol Chem
  • 1993

2 , 3 , 7 , 8tetrachlorodibenzopdioxin causes reduction in glucose transporting activities in the plasma membranes of adipose tissue and pancreas from the guinea pig

  • E Enan, Liu PCC
  • J Environ Sci Health B
  • 1992

The effect of fat cell size on subcutaneous adipose tissue metabolism

  • P Bjorntorp, U Smith
  • J Biol Chem
  • 1992

Chronic treatment with insulin selectively downregulates cell - surface GLUT 4 glucose transporters in 3 T 3L 1 adipocytes

  • IJ Kozka, AE Clark, GD Holman
  • J Biol Chem
  • 1990

Similar Papers

Loading similar papers…