Regulation of glucokinase activity in the domestic fowl.

  title={Regulation of glucokinase activity in the domestic fowl.},
  author={Hillar Klandorf and Bruce L. Clarke and Adrienne C. Scheck and James D.J. Brown},
  journal={Biochemical and biophysical research communications},
  volume={139 3},
The factors which regulate soluble and particulate glucokinase and hexokinase activity in the liver of domestic chickens has been investigated. Pretreatment with oral administration (via tube feeding) of glucose plus injection of insulin resulted in a significant increase in the activity of soluble (p less than 0.01) and particulate (p less than 0.01) glucokinase activity whereas fasting for 48 hours reduced glucokinase and hexokinase activity (p less than 0.01) in the particulate fraction only… CONTINUE READING


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